What is your greatest weakness?
My main weakness is that perhaps I pay too much attention to detail, as although it is good to do things to the best of one’s ability, sometimes I can spend too much time and energy on things which with hindsight are comparatively irrelevant. I recognise this weakness and I try to channel my energy and enthusiasm for work into helping others, for example I assist in younger years’ mathematics classes on a weekly basis, which I feel to be a more worthwhile and rewarding use of my time.
A patient is prescribed Paracetamol 1 gram four times a day as required, for one week. Paracetamol is available as a 500mg tablet. How many tablets does the patient require in one week?
There are 1000mg in 1G (ie. Two tablets per dose)
Whilst the prescription is PRN (as required), when issuing medication we must assume that the patient requires their full eligible quota.
Each dose – Patient requires 2 tablets
Each day – Patient requires (2 x4) = 8 tablets
Each week – Patient requires (8 x 7) = 56 tablets
A patient with kidney failure requires strict fluid input:output monitoring. The patient weighs 80kg and has a urine output of 0.5ml/kg/hour. The patient is required to have a positive fluid balance of 500ml/24 hours. How much should the patient drink every hour (assuming there are no additional fluid inputs/outputs)
(Provide your answer to 1 decimal place)
Urine Output in 24 hours = 0.5 x 80 x 24
Urine Output in 24 hours = 960ml
Total Required Fluid Input = 960ml + 500ml
Total Required Fluid Input (in 24 hours) = 1,460ml
Fluid Requirement/Hour = 1460/24
Fluid Requirement/Hour = 60.8ml/hour
Review the graph below and explain your findings.
(Adapted from: https://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Carbonic_anhydrase_reaction_in_tissue.svg/504px-Carbonic_anhydrase_reaction_in_tissue.svg.png)
Excellent candidates will use the ‘BlackStone Tutors Six Point Approach for Data Analysis’
Data Title (if present)
‘x’ axis and ‘y’ axis
Graphical/tabular progression shown
Physiological correlation (How can this pattern be explained biologically?)
Anomalies/additional information of note
Critical analysis of data/data source
The given plot describes how a reaction proceeds with and without an enzyme. On the x-axis, reaction coordinates are labelled and on the y-axis, energy (Activation energy) is labelled. The graph demonstrates that in the presence of an enzyme (red line), a lower activation energy is required to yield the same volume of products. Without the enzyme (blue line), additional energy must be supplied to carry out the same reaction. This is explained by the fact that in order for a chemical reaction to take place and reactants to be converted to products, chemical bonds must be broken and rearranged. The energy needed to break bonds is termed “activation energy.” Enzymes tend to offer an alternative pathway for reactions with a lower activation energy, thus reducing the amount of energy required to convert reactants to products. The graph itself is well presented and easy to understand, and is from a commonly utilised (although sometimes inaccurate) source.